In The Spotlight
DDNews Cancer Research Exclusive
Recent work with nanoparticles offers a new approach to photo-thermal cancer therapies
(Photo credit: University of Toronto)
The PEARLs (Photothermal Enhancing Auto-Regulated Liposomes) were developed by Dr. Gang Zheng of the Princess Margaret Cancer Centre and University of Toronto and colleagues, who say they overcome traditional roadblocks to penetrate deeper into tumors.
The companies will look at the potential of combining Nektar's NKTR-214 with five of Takeda's oncology compounds
Second Phase 2 clinical collaboration between the two companies is for the treatment of patients with malignant pleural mesothelioma
Small-molecule compounds demonstrate tumor regression and adaptive immune response
BMS, Foundation Medicine focus on such markers as tumor mutational burden, microsatellite instability
CGI teams up with Mendel Health to better match patients with clinical trials
Heat Biologics Inc. announced that it had reached its efficacy endpoint and met the expansion criteria to advance into Phase 2
The companies will collaborate to develop and commercialize a pan-TRK IHC test for larotrectinib
New evidence highlights significant impact in reducing burden of unnecessary chemotherapy for patients
DDNews checks in on the growing and promising activity around immuno-oncology
by Dr. Alexey Eliseev, RXi
The ďWar on CancerĒ declared by the National Cancer Act of 1971 proceeded through a series of evolutionary developments in chemotherapy, radiation treatments and targeted therapies, but until recently was only marginally successful in extending the lives of late-stage cancer patients. A major breakthrough has been achieved over the last decade with the development of immunotherapeutic treatments that empower a patientís own immune cells to destroy tumors

by Dr. Brad Thompson, Oncolytics
During these heady and still-early days in the age of clinical studies involving immunotherapy, it is useful to ponder some of the outstanding questions these studies raise

by Laurie Heilmann
As the design of anticancer agents has evolved, the processes, methods and equipment used to aid the fight against cancer have too, leading to the resurgence of immunotherapy as a powerful way of fighting cancer

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