CHICAGO—The 2016 American Society of Clinical Oncology (ASCO) meeting saw Vice President Joe Biden thank oncologists for their work and commitment and encourage the development of new ideas to help advance the National Cancer Moonshot Initiative. The vice president touched on the four top priorities for the Moonshot program, which include significant new federal investment in cancer research; enhanced sharing of research and patient data; increased use of team-based approaches that harness different medical and scientific disciplines; and new approaches to developing and recruiting for clinical trials. Another topic of concern for him was the importance of data-sharing and initiatives that are underway to that end, such as ASCO’s CancerLinQ and the National Cancer Institute’s newly launched effort.