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Expanded mouse models from JAX
December 2016
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BAR HARBOR, Maine—The Jackson Laboratory (JAX) has expanded its offerings with the launch of its Model Generation Services, a comprehensive suite of genome-editing technologies that can enable custom-made mouse models for the study of disease. JAX has also added CRISPR/Cas9-mediated gene editing into its development of custom-built mouse models. Model Generation Services include CRISPR/Cas9 Model Generation, to enable customers to develop knock out and knock in models; Transgenic Model Services, for overexpressing novel gene constructs in defined inbred strain backgrounds via pronuclear microinjection; and ES Cell Microinjection Services, for the creation of large, targeted genomic mutations in various genetic backgrounds.
 
“CRISPR technology has transformed genetic engineering in nearly all biological systems,” said JAX President and CEO Dr. Edison Liu. “Applying this technique to build more predictive preclinical models and precise patient treatment strategies will be pivotal in developing the next generation of predictive models for the new era of personalized medicine.”

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