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One down, two to go
November 2019
SHARING OPTIONS:

GLASGOW, Scotland—The first cohort of patients for a Phase 2a clinical study of MGB Biopharma’s MGB-BP-3 antibiotic has completed treatment, the company reported last month. The open-label trial is evaluating the safety, tolerability and efficacy of incremental doses of MGB-BP-3 in patients with Clostridium difficile-associated disease (CDAD), and thus far the data point to high efficacy and good tolerability in the first cohort. Recruitment for the second of three cohorts is underway in the United States and Canada. MGB-BP-3 has a novel mode of action and has demonstrated strong bactericidal activity against BI/NAP1/027, the most virulent strain of C. difficile and one that is largely antibiotic-resistant.
 
Dr. Miroslav Ravic, CEO of MGB Biopharma, said in part that, “Given its unique properties, we remain confident that MGB-BP-3 could represent a new paradigm for the treatment of CDAD, a potentially life-threatening infection.”

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