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MIMETAS to pursue kidney-on-a-chip model with $1.6M
November 2014
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LEIDEN, the Netherlands—MIMETAS has announced the receipt of $1.6 million in funding to develop a kidney-on-a-chip for toxicological use and will collaborate in a consortium with Radboudumc and FHNW. This funding stems from the NephroTube CRACK IT Challenge, which is organized by the United Kingdom’s National Centre for the Replacement, Refinement and Reduction of Animals in Research and supports the development of a microfluidic renal model that can predict renal toxicity in preclinical development. The funds will allow the consortium to develop, analyze and validate a high- throughput kidney-on-a-chip model through the combination of MIMETAS’ OrganoPlate 3D-culturing technology and the human renal cell line ciPTEC. This model will aid in the detection of renal tubular injury seen in drug-induced nephrotoxicity, and the early prediction capabilities of the model will allow for fewer animal experiments.

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