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High-throughput gene expression, Beckman Coulter
June 2005
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Beckman Coulter, Inc. has launched the GenomeLab GeXP Genetic Analysis System which provides high-throughput, quantitative gene expression using scalable, multiplexed PCR. The system's patented priming strategy overcomes the biases that normally limit standard multiplexed PCR analysis to just a few genes at a time. GenomeLab GeXP permits the analysis of more genes per reaction and more samples per run, removing bottlenecks in gene expression studies for drug discovery and development research. The system can run two 96-well plates in 24 hours, and look at the expression of 20 to 35 genes in a single reaction per well. The GeXP uses a two-primer process with gene-specific universal primers that overcome biases from primer-primer reactions, primer-product cross-reactions and from variations in amplification efficiency. This priming strategy, combined with single endpoint fluorescence detection, enables higher levels of quantitation and multiplexing. The system's software tools support the technique from primer design through data analysis.
 
Beckman Coulter
800.742.2345

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