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Detect inducers and inhibitors of endothelial cell tube formation
June 2007
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Trevigen's Cultrex Angiogenesis System (CAS) HT Tube Formation Kit allows for the detection of inducers and inhibitors of endothelial cell tube formation. The kit contains Cultrex Reduced Growth Factor (RGF) Basement Membrane Extract (BME), a soluble form of basement membrane purified from Engelbreth-Holm-Swarm (EHS) tumor, which gels at room temperature to form a reconstituted protein matrix. Sulforaphane, a naturally occurring cancer chemopreventive agent, is provided as a control for inhibition of in vitro endothelial cell tube formation on Cultrex RGF BME. Calcein AM is provided as a fluorescent stain to view live tube formation. Alternately, cells can be fixed and visualized using Trevigen's Cell Staining Solution. Trevigen's CAS HT Tube Formation Kit provides a cost-effective method for investigation of prospective angiogenesis inhibitors and inducers in a 96-well format.
 
Trevigen Inc.
800-873-8443

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