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Real-time PCR detection system
April 2009

Bio-Rad Laboratories Inc.

Bio-Rad Laboratories Inc. has announced the launch of its new Bio-Rad CFX384 real-time PCR detection system as well as its new CFX Manager software, Security Edition. CFX Manager can be used to ensure compliance with the regulations published by the U.S. Food and Drug Administration for secure handling of electronic records (as outlined in Title 21 of the Code of Federal Regulations, 21 CFR Part 11). Researchers have access to high-throughput real-time PCR in a 384-well format. The system reads each well individually with high sensitivity and no cross-talk to deliver optimal quantitative results. Multiple data acquisition modes let runs be tailored to suit any application and the compact design fits any laboratory setting. The CFX384 system can be operated in several control configurations. Researchers can either run a stand-alone system without a computer or up to four instruments from one computer (either PC or Mac). The CFX384 system provides multiple scan modes for data acquisition, so runs can be tailored to different detection chemistries. SYBR Green I and single-color FAM protocols are completed in less time using the SYBR/FAM-only scan mode, which collects data from channel one for all 384 wells in just eight seconds. In multi-channel scan mode, the system detects fluorescence from channels one through four for all 384 wells in less than 20 seconds, enabling four-target discrimination in a single well. The CFX384 real-time PCR detections system's optics shuttle includes a channel dedicated for single-color FRET (Fluorescence Resonance Energy Transfer) experiments, further expanding experimental options. The CFX384 real-time PCR detection system can be controlled by CFX Manager software (version 1.1).
Bio-Rad Laboratories Inc.



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