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Biosensor for kinetic analysis and screening of human IgG antibodies
April 2009
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ForteBio Inc.

ForteBio Inc. has announced the launch of its Anti-Human IgG Fc Capture (AHC) biosensor for use on the company's Octet instrumentation platform. The new biosensor enables more cost-effective, easy-to-use and rapid kinetic characterization and screening of human IgG antibodies and other Fc-containing proteins—important components in biomolecular therapeutic development—and further broadens the menu of Octet system applications. The new AHC biosensor leverages the Octet platform's proprietary Bio-Layer Interferometry technology to enable kinetic profiling of human IgGs against analyte in a microplate well format. The biosensor surface can also be used to conduct ligand inhibition assays by expanding the variables that can be measured, such as blocking and unblocking analytes, affinity, and association and dissociation rates. The new AHC biosensor further expands the capabilities of the Octet platform, which already supports quantitation of human IgG using Protein A. ForteBio's Octet biosensors are configured in a standard 96-well format. Its biosensors simplify quantitation and kinetic characterization by eliminating throughput limitations of traditional SPR-based systems. Octet biosensors are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding.

ForteBio Inc.
650-322-1360
www.fortebio.com

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