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Faster, safer and cleaner reactions
August 2009
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Syrris

Africa is a range of fully automated, flexible and easy-to-use microreactor flow systems. The Africa system allows R&D chemists working in discovery and process development to accelerate compound synthesis and reaction optimization. Fully automated hardware is controlled by the Africa software to enable unattended runs. Reagents are injected and products are collected automatically. Increase reaction rates more than one hundred-fold by superheating reactions significantly above reflux e.g. dichloromethane to 100 degrees Celsius, acetonitrile to 150 degrees Celsius and water to 170 degrees Celsius. Reduce impurities via reproducible reaction control and optional use of solid phase reagents, catalysts or scavengers. The Flow Liquid Liquid Extraction Module (FLLEX) enables two immiscible phases to be mixed and separated in flow, immediately following the reaction. A sample of reaction mixture can be taken, diluted and analyzed by HPLC in an entirely automated fashion. Excellent correlation with shake flask method. Only small amounts of material react at any time, minimizing exotherms and the quantity of any hazardous intermediates.

Syrris
617-848-2997
www.syrris.com


 

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