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Universal, Label-free, Cell-based Assay Technology, MDS Sciex
October 2005
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MDS Sciex, the analytical instruments division of MDS Inc., launched the CellKey System for measurement of endogenous cell surface receptor activation in live cells and gneration of data that enables identification of the receptor coupling mechanism of unknown receptors (e.g., orphan G protein-coupled receptors). The CellKey System is based on cellular dielectric spectroscopy (CDS's) technology, an approach that removes the requirement for fluorescent or radio-labeled markers from the drug discovery workflow, thereby simplifying assay development. The sensitivity of CDS' impedance-based measurement system enables the measurement of receptor targets in whole live cells and the generation of data that is more biorelevant than in other cellular screening systems. MDS Sciex claims that this system can simplify assay design activities, address many of the bottlenecks currently experienced within secondary screening and lead optimization, and ultimately enable researchers to develop important new medicines more rapidly.
 
MDS Sciex
866-MYSCIEX

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