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New answers about antimicrobial resistance
March 2019
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SEATTLE—A recent antimicrobial resistance (AMR) study led by scientists at the University of Idaho has described a new method for linking AMR genes and other mobile genetic elements to their hosts straight from microbiome samples and without the need for culturing constituent microbes. This method, details of which were published in bioRxiv, is based on Phase Genomics’ ProxiMeta Hi-C microbiome discovery platform. The inability to identify the hosts responsible for spreading AMR within complex microbiome communities is a leading problem. This work offers a method of detecting how AMR spreads within microbial communities, and also provides hundreds of new bacterial genomes, with the data used to “directly assign sequences like plasmids and AMR genes to their hosts, even when these hosts were novel strains and species,” as noted in a press release.

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