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Novel HAMA blocker for reduction of immunoassay interference
January 2010
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amsbio
 
amsbio has introduced TRU Block, a highly potent reagent that actively blocks the heterophilic antibody (HA) interference in immunoassays, including Human Anti-Mouse Antibody (HAMA) interference. While traditional Mouse IgG reagents which inhibit HAMA by serving as antigens of HAMA, TRU Block works by using a proprietary active mechanism and is five to 20 times more effective than Mouse IgG on HAMA blocking, thereby reducing blocker usage. TRU Block works on HAMA as well as other types of HA, while Mouse IgG is effective only on HAMA. Extensive quality control, including a HAMA blocking functional assay, purity and bioburden testing, ensures that every batch of TRU Block is well characterized. Lot-to-lot consistency reduces the need for adjusting assay reagents to optimize performance.
 
amsbio
 

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