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Mouse monoclonal antibody for MS research
December 2010
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AnaSpec  
 
AnaSpec has announced the release of the mouse monoclonal Anti-MOG (1-125). Anti-MOG was produced by immunizing Balb/c mice with recombinant MOG (1-125) as an antigen. It is supplied as purified mouse IgG1, 250 ml in 40 mM MOPS (pH 7.5) with 50 percent glycerol containing 0.1 percent sodium azide and 0.1 percent BSA. MOG protein constitutes only 0.01 percent to 0.5 percent of the CNS myelin proteins, has a mass of 27kDa, and is located in the outermost layer of myelin sheath (1-6). Mouse MOG is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination (1-4). Autoantibody response to mouse MOG has been observed in induced experimental autoimmune encephalomyelitis (EAE) in C57/BL6, 129/Sv, B6, and SJL mice (3-4).
 
AnaSpec
(510) 791-9560
www.anaspec.com
 

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